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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POM121L2 All Species: 6.36
Human Site: S458 Identified Species: 17.5
UniProt: Q96KW2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KW2 NP_258443 971 103081 S458 P T S H L S A S A P P D A T S
Chimpanzee Pan troglodytes XP_518297 971 103377 S458 P T S H L S A S A P P D A T S
Rhesus Macaque Macaca mulatta XP_001094164 974 103469 A461 S P T P H L S A S A P P D A T
Dog Lupus familis XP_546930 890 89245 G378 S L S S S Q S G A L P G A S S
Cat Felis silvestris
Mouse Mus musculus Q5SW25 972 103201 T459 V I N P T A P T T Q S T L V G
Rat Rattus norvegicus P52591 1199 120766 P601 A T V A A P S P P K T P S L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514514 686 70317 P174 R S L N A H C P D D S W S K R
Chicken Gallus gallus XP_415711 809 79517 T297 A A A V P T T T P V F K P I F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696713 1201 123069 P667 M G T T T A A P A V P V S S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 91.2 31 N.A. 49.4 34.7 N.A. 25.7 24.7 N.A. 25 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.6 94.1 43.9 N.A. 62 45.5 N.A. 36.2 37.6 N.A. 37.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 33.3 N.A. 0 6.6 N.A. 0 0 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 40 46.6 N.A. 20 20 N.A. 20 20 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 12 12 12 23 23 34 12 45 12 0 0 34 12 0 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 12 12 0 23 12 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 12 % F
% Gly: 0 12 0 0 0 0 0 12 0 0 0 12 0 0 12 % G
% His: 0 0 0 23 12 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 12 0 12 0 12 0 % K
% Leu: 0 12 12 0 23 12 0 0 0 12 0 0 12 12 23 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 23 12 0 23 12 12 12 34 23 23 56 23 12 0 0 % P
% Gln: 0 0 0 0 0 12 0 0 0 12 0 0 0 0 0 % Q
% Arg: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % R
% Ser: 23 12 34 12 12 23 34 23 12 0 23 0 34 23 34 % S
% Thr: 0 34 23 12 23 12 12 23 12 0 12 12 0 23 12 % T
% Val: 12 0 12 12 0 0 0 0 0 23 0 12 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _